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The gluten challenge test (short: ''gluten challenge'') is a medical test in which gluten-containing foods are consumed and (re-)occurrence of symptoms is observed afterwards to determine whether and how much a patient reacts to these foods. The test is usually performed to test patients with suspected or confirmed gluten-related disorders such as coeliac disease or non-coeliac gluten sensitivity (NCGS). To assess gluten intolerance, the organism is "challenged" by ingesting gluten-containing foods, even though the patient has shown or reported an intolerance to such foods. ==History== Before serological and biopsy-based diagnosis of coeliac disease was available, a gluten challenge test was a prerequisite for diagnosis of coeliac disease. Today, with serological testing and biopsy with histological testing being available for diagnosing coeliac disease, patients with suspected coeliac disease are strongly advised to undergo serological and, if necessary, biopsy testing before undertaking a gluten-free diet. A gluten challenge is no longer necessary for those patients whose diagosis of coeliac disease is based on findings of a flat mucosa (villous atrophy) under a normal gluten-containing diet. A gluten challenge may still be necessary for certain patients groups, for example for patients who had started a gluten-free diet without a biopsy-confirmed diagnosis of coeliac disease. In recent years, a gluten challenge is increasingly also used for diagnosing non-coeliac gluten sensitivity, given that there are so far no biomarkers for its diagnosis. 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Gluten challenge test」の詳細全文を読む スポンサード リンク
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